If you are using frozen shrimp, thaw them in the refrigerator a day before preparing them.
Place a cast iron skillet on the stove over medium heat.
When the pan is hot, add the butter, garlic powder, onion powder, cayenne, old bay, salt, and pepper, and cook until the butter melts.
Add the shrimp to the skillet and stir continuously until the shrimp are fully cooked or when the flesh becomes opaque, turns bright pink, and the tails start to curl.